Balaji M. Agoram, Rhys Jones & Piet H van der Graaf, A Physiologically-Based Mathematical Model to Predict Lung Retention and Inhaled Pharmacokinetics of Therapeutic Candidates
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Brenda CM de Winter(1), Ferdi Sombogaard(1), Reinier M van Hest(1), Teun van Gelder(1,2), Ron AA Mathot(1) Mechanism-based pharmacokinetic modelling of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients
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Dickinson GL, Jackson KJ Prediction of a Metabolic Drug-Drug Interaction in a Virtual Human Population using in vitro Enzyme Kinetic Information
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Hannah M Jones Use of PBPK modelling in drug discovery at Pfizer
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C. Becker(1), S. Willmann (1), T. Eissing (1), R. Burghaus (2), J. Lippert(1), G. Ahr(2), H. Stass(2) Whole-Body Physiologically-Based Pharmacokinetic (WB-PBPK) Modeling of Moxifloxacin (MFX) to Support a Translational Approach in Pediatric Study Design
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Viglinskaya A.O., Kolyvanov G.B., Mesonzhnik N.V., Baranov P.A., Litvin A.A., Zherdev V.P., Rodchenkov G.M. A physiology-based pharmacokinetic model describing the disposition of a novel selective anxiolytic drug afobazole and its metabolites in rats.
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S.Y. Amy Cheung (1), Malcolm Rowland (2), Leon Aarons (2), Trudy Rodgers (1), Iva Gueorguieva (3) Development of a closed loop whole body (WB) physiologically based pharmacokinetic model (PBPK) of beta-blockers in the rat
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C. Gérard (1), N. Bleyzac (2), P. Girard (1), B. Tranchand (1), G. Freyer (1), Y. Bertrand (2), M. Tod (1). Influence of cyclosporin infusion duration on efficacy in paediatric bone marrow transplantation: analysis by a PBPK model
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C. Gérard (1), N. Bleyzac (2), P. Girard (1), B. Tranchand (1), G. Freyer (1), Y. Bertrand (2), M. Tod (1). Link between cyclosporin exposure in tissues and graft versus host disease in paediatric bone marrow transplantation: analysis by a PBPK model
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N.H. Prins (1), A. Cleton (2), M.O. Magnusson (2) , P. Johnson (2), A. Heatherington (2) Characterization of the population pharmacokinetics of UK-369,003 using a semi-mechanistic model
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A. Edginton (1), C. Boscarino (2), P. Sidhu (1), W. Riggs (3), A. Szeitz (3), B. Cheung (2), H. Peng (2) Parameterization of a physiologically-based pharmacokinetic (PBPK) model for the simulation of ibuprofen pharmacokinetics under exercise and heat stress with validation from clinical data
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